Gout

what’s in and what’s out

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Case study: Gout

Sione Fonoti is a 53-year-old Samoan male who presents in your practice after experiencing what he describes as intense pain in his big toe, and moderate pain in his knee. He says that the pain woke him up the previous morning at 4:00 am and increased in intensity throughout the day. Sione booked an appointment with you today at 10:00 am (30 hours after the pain began).

Medical history

Potential previous flare

  • Sione reports having had similar symptoms in his first metatarsophalangeal (MTP) joint on his left foot five months ago
  • He did not seek medical attention for this event as his older brother told him that he sometimes gets the same pain and it “goes away after a few days if you take lots of ibuprofen"
  • Sione’s symptoms resolved completely after five days of over-the-counter ibuprofen-use

Hypertension

  • Sione was diagnosed with hypertension three years ago after a routine blood pressure check; his blood pressure was 148/94 mmHg at the time
  • You assessed his HbA1C and lipids at the time of this diagnosis and every six months since; these measurements have remained at the high end of normal limits
  • After trialling lifestyle changes for six months, a decision was made to initiate antihypertensive treatment; Sione has consistently achieved blood pressure measurements <140/90 mmHg for the past year and a half

Medicines

  • Quinapril + hydrochlorothiazide 10/12.5 mg daily

Family history

  • Based on your discussion today, Sione calls his older brother for clarification, who confirms that he has been diagnosed with gout and hypertension
    • Sione’s brother is taking an antihypertensive medicine but has not been prescribed a urate-lowering medicine
  • No known family history of diabetes or ischaemic heart disease

Social history

  • Sione works as a chef in a local seafood restaurant
  • He describes being “on-the-go” at work, but is sedentary in his spare time
  • During a discussion about his diet, Sione says he eats a diverse range of food because of his job and general interest in cooking, however, seafood constitutes a large proportion of his diet
  • Sione was a daily smoker during his twenties and thirties, but has been a non-smoker for the past 15 years
  • He usually has between 10–12 standard drinks per week and he is largely a beer drinker; he sometimes has more if it is a special occasion

Relevant examination findings:

  • BMI: 33.31 (height: 175 cm; Weight: 102 kg)
  • Blood pressure: 136/84 mmHg
  • Heart rate: 94 bpm (regular rhythm)
  • Clinical evaluation: in addition to the severe pain being reported, Sione has:
    • An obvious limp when he walks into your office and says he was unable to go to work yesterday or put his shoe on
    • Redness, swelling and warmth at the first MTP joint on his left foot, and similar – but less severe – symptoms at the knee on the same leg; Sione indicates he has mild tenderness in his knee but is very tender to palpation over the first MTP joint
    • No obvious tophi

Ranking:

Well done!